A dataset of 29 trials comparing three antiparkinsonian
interventions with placebo (a star-shaped network) in patients with later
Parkinson's disease. The analysed continuous outcome is the change from
baseline of patient off-time reduction.
A data frame with 29 rows of arm-based data and 11 columns (maximum
number of 2 arms).
Source
Stowe R, Ives N, Clarke CE, et al. Meta-analysis of the comparative efficacy
and safety of adjuvant treatment to levodopa in later Parkinson's disease.
Mov Disord 2011;26(4):587–98. doi: 10.1002/mds.23517
Details
The interventions have been coded as follows: 1, placebo plus
levodopa (PBO+LD); 2, dopamine agonist plus levodopa (DA+LD);
3, catechol-O-methyl transferase inhibitors plus levodopa (COMBI+LD); and
4, monoamine oxidase type B inhibitors plus levodopa (MAOBI+LD).